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NF is one of the most common single gene human diseases; around 1 in 2,500 4,000 live births are affected by NF 1, whereas NF 2 occurs in about 1 in 50,000 120,000. Both type 1 and 2 are autosomal dominant conditions, moncler womens bomber jacket
meaning that only one copy of the mutated gene need be inherited to pass the disorder. A child of a parent with neurofibromatosis and an unaffected parent will have a 50% chance of inheriting the disorder. The gene responsible for NF 1 and possibly NF 2 is thought to function as a tumor suppressor gene.
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